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Monday, January 12, 2015

Sanofi and Regeneron Announce Positive Topline Results from First Phase 3 Trials Evaluating Monthly Dosing of Alirocumab in Patients with Hypercholesterolemia

Tarrytown, New York and Paris - January 9, 2015 - Sanofi and Regeneron Pharmaceuticals, Inc.

today announced that two new ODYSSEY trials, which are the first Phase 3 trials to assess

alirocumab administered every four weeks, met their primary efficacy endpoints. The trials

compared the reduction from baseline in low-density lipoprotein cholesterol (LDL-C, or “bad”

cholesterol) at 24 weeks with alirocumab versus placebo in patients with hypercholesterolemia.

Alirocumab is an investigational monoclonal antibody targeting PCSK9 (proprotein convertase

subtilisin/kexin type 9). 



en.sanofi.com/Images/38079_20150109_AlirocumabTopline_en.pdf

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